Structural Recognition and Binding Pattern Analysis of Human Topoisomerase II Alpha with Steroidal Drugs: In Silico Study to Switchover the Cancer Treatment

BACKGROUND AND OBJECTIVE: Topoisomerase TOP-IIA (TTOP-IIA) is widely used as a significant target for cancer therapeutics because of its involvement in cell proliferation. Steroidal drugs have been suggested for breast cancer treatment as aromatase enzymes inhibitors . TTOP-IIA inhibitors can be use...

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Detalles Bibliográficos
Autor principal: Jamal, Qazi Mohammad Sajid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541882/
https://www.ncbi.nlm.nih.gov/pubmed/32458643
http://dx.doi.org/10.31557/APJCP.2020.21.5.1349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541882/
https://www.ncbi.nlm.nih.gov/pubmed/32458643
http://dx.doi.org/10.31557/APJCP.2020.21.5.1349

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