Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model

Systemic Lupus Erythematosus (SLE) is a chronic inflammatory autoimmune disease in which type I interferons (IFN) play a key role. The IFN response can be triggered when oxidized DNA engages the cytosolic DNA sensing platform cGAS-STING, but the repair mechanisms that modulate this process and gover...

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Detalles Bibliográficos
Autores principales: Tumurkhuu, Gantsetseg, Chen, Shuang, Montano, Erica N., Ercan Laguna, Duygu, De Los Santos, Gabriela, Yu, Jeong Min, Lane, Malcolm, Yamashita, Michifumi, Markman, Janet L., Blanco, Luz P., Kaplan, Mariana J., Shimada, Kenichi, Crother, Timothy R., Ishimori, Mariko, Wallace, Daniel J., Jefferies, Caroline A., Arditi, Moshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541920/
https://www.ncbi.nlm.nih.gov/pubmed/33072095
http://dx.doi.org/10.3389/fimmu.2020.554725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541920/
https://www.ncbi.nlm.nih.gov/pubmed/33072095
http://dx.doi.org/10.3389/fimmu.2020.554725

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