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Ectopic bone formation and systemic bone loss in a transmembrane TNF-driven model of human spondyloarthritis
BACKGROUND: The transmembrane-TNF transgenic mouse, TgA86, has been shown to develop spontaneously peripheral arthritis with signs of axial involvement. To assess similarity to human spondyloarthritis, we performed detailed characterization of the axial, peripheral, and comorbid pathologies of this...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542121/ https://www.ncbi.nlm.nih.gov/pubmed/33023659 http://dx.doi.org/10.1186/s13075-020-02327-4 |