Ectopic bone formation and systemic bone loss in a transmembrane TNF-driven model of human spondyloarthritis

BACKGROUND: The transmembrane-TNF transgenic mouse, TgA86, has been shown to develop spontaneously peripheral arthritis with signs of axial involvement. To assess similarity to human spondyloarthritis, we performed detailed characterization of the axial, peripheral, and comorbid pathologies of this...

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Detalles Bibliográficos
Autores principales: Christodoulou-Vafeiadou, Eleni, Geka, Christina, Ntari, Lydia, Kranidioti, Ksanthi, Argyropoulou, Eleni, Meier, Florian, Armaka, Marietta, Mourouzis, Iordanis, Pantos, Constantinos, Rouchota, Maritina, Loudos, George, Denis, Maria C., Karagianni, Niki, Kollias, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542121/
https://www.ncbi.nlm.nih.gov/pubmed/33023659
http://dx.doi.org/10.1186/s13075-020-02327-4

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