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Immediate and durable effects of maternal tobacco consumption alter placental DNA methylation in enhancer and imprinted gene-containing regions

BACKGROUND: Although exposure to cigarette smoking during pregnancy has been associated with alterations of DNA methylation in the cord blood or placental cells, whether such exposure before pregnancy could induce epigenetic alterations in the placenta of former smokers has never been investigated....

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Detalles Bibliográficos
Autores principales: Rousseaux, Sophie, Seyve, Emie, Chuffart, Florent, Bourova-Flin, Ekaterina, Benmerad, Meriem, Charles, Marie-Aline, Forhan, Anne, Heude, Barbara, Siroux, Valérie, Slama, Remy, Tost, Jorg, Vaiman, Daniel, Khochbin, Saadi, Lepeule, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542140/
https://www.ncbi.nlm.nih.gov/pubmed/33023569
http://dx.doi.org/10.1186/s12916-020-01736-1