Yield and Utility of Germline Testing Following Tumor Sequencing in Patients With Cancer

IMPORTANCE: Both germline genetic testing and tumor DNA sequencing are increasingly used in cancer care. The indications for testing and utility of these 2 tests differ, and guidelines recommend that germline analysis follow tumor sequencing in certain patients to determine whether particular varian...

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Detalles Bibliográficos
Autores principales: Lincoln, Stephen E., Nussbaum, Robert L., Kurian, Allison W., Nielsen, Sarah M., Das, Kingshuk, Michalski, Scott, Yang, Shan, Ngo, Nhu, Blanco, Amie, Esplin, Edward D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2020
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542302/
https://www.ncbi.nlm.nih.gov/pubmed/33026450
http://dx.doi.org/10.1001/jamanetworkopen.2020.19452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542302/
https://www.ncbi.nlm.nih.gov/pubmed/33026450
http://dx.doi.org/10.1001/jamanetworkopen.2020.19452

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