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ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells

The intracellular protozoan parasite Toxoplasma gondii is capable of infecting most nucleated cells, where it survives in a specially modified compartment called the parasitophorous vacuole (PV). Interferon gamma (IFN-γ) is the major cytokine involved in activating cell-autonomous immune responses t...

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Detalles Bibliográficos
Autores principales: Bhushan, Jaya, Radke, Joshua B., Perng, Yi-Chieh, Mcallaster, Michael, Lenschow, Deborah J., Virgin, Herbert W., Sibley, L. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542356/
https://www.ncbi.nlm.nih.gov/pubmed/33024031
http://dx.doi.org/10.1128/mBio.00852-20