Targeting tumor hypoxia and mitochondrial metabolism with anti-parasitic drugs to improve radiation response in high-grade gliomas

High-grade gliomas (HGGs), including glioblastoma and diffuse intrinsic pontine glioma, are amongst the most fatal brain tumors. These tumors are associated with a dismal prognosis with a median survival of less than 15 months. Radiotherapy has been the mainstay of treatment of HGGs for decades; how...

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Detalles Bibliográficos
Autores principales: Mudassar, Faiqa, Shen, Han, O’Neill, Geraldine, Hau, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542384/
https://www.ncbi.nlm.nih.gov/pubmed/33028364
http://dx.doi.org/10.1186/s13046-020-01724-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542384/
https://www.ncbi.nlm.nih.gov/pubmed/33028364
http://dx.doi.org/10.1186/s13046-020-01724-6

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