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NFAT2 overexpression suppresses the malignancy of hepatocellular carcinoma through inducing Egr2 expression

BACKGROUND: Nuclear factor of activated T cells 2 (NFAT2) has been reported to regulate the development and malignancy of few tumors. In this study, we aimed to explore the effect of NFAT2 expression on cell fate of HepG2 cell and its potential mechanisms. METHODS: Firstly, the pcDNA3.1-NFAT2 plasmi...

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Detalles Bibliográficos
Autores principales: Wang, Jian, Zhang, Yamin, Liu, Lei, Cui, Zilin, Shi, Rui, Hou, Jiancun, Liu, Zirong, Yang, Long, Wang, Lianjiang, Li, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542386/
https://www.ncbi.nlm.nih.gov/pubmed/33023539
http://dx.doi.org/10.1186/s12885-020-07474-0