CRISPRoff enables spatio-temporal control of CRISPR editing

Following introduction of CRISPR-Cas9 components into a cell, genome editing occurs unabated until degradation of its component nucleic acids and proteins by cellular processes. This uncontrolled reaction can lead to unintended consequences including off-target editing and chromosomal translocations...

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Detalles Bibliográficos
Autores principales: Carlson-Stevermer, Jared, Kelso, Reed, Kadina, Anastasia, Joshi, Sahil, Rossi, Nicholas, Walker, John, Stoner, Rich, Maures, Travis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542431/
https://www.ncbi.nlm.nih.gov/pubmed/33028827
http://dx.doi.org/10.1038/s41467-020-18853-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542431/
https://www.ncbi.nlm.nih.gov/pubmed/33028827
http://dx.doi.org/10.1038/s41467-020-18853-3

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