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GDF15 Repression Contributes to 5-Fluorouracil Resistance in Human Colon Cancer by Regulating Epithelial-Mesenchymal Transition and Apoptosis

Chemotherapy based on 5-fluorouracil (5-FU) is the standard approach for colon cancer treatment, and resistance to 5-FU is a significant obstacle in the clinical treatment of colon cancer. However, the mechanisms underlying 5-FU resistance in colon cancer cells remain largely unknown. This study aim...

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Detalles Bibliográficos
Autores principales: Wang, Bin, Ma, Nina, Zheng, Xixi, Li, Xiao, Ma, Xiao, Hu, Jiexuan, Cao, Bangwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542494/
https://www.ncbi.nlm.nih.gov/pubmed/33062674
http://dx.doi.org/10.1155/2020/2826010