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Identification of ATP8B1 as a Tumor Suppressor Gene for Colorectal Cancer and Its Involvement in Phospholipid Homeostasis

Homeostasis of membrane phospholipids plays an important role in cell oncogenesis and cancer progression. The flippase ATPase class I type 8b member 1 (ATP8B1), one of the P4-ATPases, translocates specific phospholipids from the exoplasmic to the cytoplasmic leaflet of membranes. ATP8B1 is critical...

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Detalles Bibliográficos
Autores principales: Deng, Li, Niu, Geng-Ming, Ren, Jun, Ke, Chong-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542516/
https://www.ncbi.nlm.nih.gov/pubmed/33062669
http://dx.doi.org/10.1155/2020/2015648