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Chromodomain Helicase DNA-Binding Protein 5 Inhibits Renal Cell Carcinoma Tumorigenesis by Activation of the p53 and RB Pathways

Chromodomain helicase DNA-binding protein 5 (CHD5) plays a crucial tumor suppressor role in multiple types of tumors. For this study, we investigated its clinical significance and the molecular mechanism(s) underlying tumorigenesis in renal cell carcinoma (RCC). Initially, CHD5 expression was assess...

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Detalles Bibliográficos
Autores principales: Huang, Sheng, Yan, Qitao, Xiong, Shilin, Peng, Yiqi, Zhao, Rui, Liu, Chunxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542531/
https://www.ncbi.nlm.nih.gov/pubmed/33062682
http://dx.doi.org/10.1155/2020/5425612