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Probing the 14-3-3 Isoform-Specificity Profile of Protein–Protein Interactions Stabilized by Fusicoccin A

[Image: see text] Fusicoccin A (FC) is a fungal phytotoxin that stabilizes protein–protein interactions (PPIs) between 14-3-3 adapter proteins and their phosphoprotein interaction partners. Recently, FC has emerged as an important chemical probe of human 14-3-3 PPIs involved in cancer and neurobiolo...

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Detalles Bibliográficos
Autores principales: Sengupta, Ananya, Liriano, Josue, Bienkiewicz, Ewa A., Miller, Brian G., Frederich, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542595/
https://www.ncbi.nlm.nih.gov/pubmed/33043180
http://dx.doi.org/10.1021/acsomega.0c01454