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Analysis of the molecular nature associated with microsatellite status in colon cancer identifies clinical implications for immunotherapy

BACKGROUND: Microsatellite instability in colon cancer implies favorable therapeutic outcomes after checkpoint blockade immunotherapy. However, the molecular nature of microsatellite instability is not well elucidated. METHODS: We examined the immune microenvironment of colon cancer using assessment...

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Detalles Bibliográficos
Autores principales: Bao, Xuanwen, Zhang, Hangyu, Wu, Wei, Cheng, Shaobing, Dai, Xiaomeng, Zhu, Xudong, Fu, Qihan, Tong, Zhou, Liu, Lulu, Zheng, Yi, Zhao, Peng, Fang, Weijia, Liu, Fanglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542666/
https://www.ncbi.nlm.nih.gov/pubmed/33028695
http://dx.doi.org/10.1136/jitc-2020-001437