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Tumor-draining lymph node is important for a robust abscopal effect stimulated by radiotherapy

BACKGROUND: Radiotherapy (RT) has been shown to stimulate an antitumor immune response in irradiated tumors as well as unirradiated distant sites (abscopal effect). Previous studies have demonstrated a role for the tumor-draining lymph node (LN) in mediating an anti-programmed death-1 (PD-1)/program...

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Detalles Bibliográficos
Autores principales: Buchwald, Zachary S, Nasti, Tahseen H, Lee, Judong, Eberhardt, Christiane S, Wieland, Andreas, Im, Se Jin, Lawson, David, Curran, Walter, Ahmed, Rafi, Khan, Mohammad K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542667/
https://www.ncbi.nlm.nih.gov/pubmed/33028691
http://dx.doi.org/10.1136/jitc-2020-000867