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Integration of anatomy ontology data with protein–protein interaction networks improves the candidate gene prediction accuracy for anatomical entities

BACKGROUND: Identification of genes responsible for anatomical entities is a major requirement in many fields including developmental biology, medicine, and agriculture. Current wet lab techniques used for this purpose, such as gene knockout, are high in resource and time consumption. Protein–protei...

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Detalles Bibliográficos
Autores principales: Fernando, Pasan C., Mabee, Paula M., Zeng, Erliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542696/
https://www.ncbi.nlm.nih.gov/pubmed/33028186
http://dx.doi.org/10.1186/s12859-020-03773-2