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Efficacy and safety-in analysis of short-course radiation followed by mFOLFOX-6 plus avelumab for locally advanced rectal adenocarcinoma

BACKGROUND: Neoadjuvant chemotherapy and short-course radiotherapy followed by resection has been gaining recognition in the treatment of rectal cancer. Avelumab is a fully human immunoglobulin that binds Programmed Death-Ligand 1 (PD-L1) and prevents the suppression of the cytotoxic T cell immune r...

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Detalles Bibliográficos
Autores principales: Shamseddine, Ali, Zeidan, Youssef H., El Husseini, Ziad, Kreidieh, Malek, Al Darazi, Monita, Turfa, Rim, Kattan, Joseph, Khalifeh, Ibrahim, Mukherji, Deborah, Temraz, Sally, Alqasem, Kholoud, Amarin, Rula, Al Awabdeh, Tala, Deeba, Samer, Jamali, Faek, Mohamad, Issa, Elkhaldi, Mousa, Daoud, Faiez, Al Masri, Mahmoud, Dabous, Ali, Hushki, Ahmad, Jaber, Omar, Charafeddine, Maya, Geara, Fady
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542723/
https://www.ncbi.nlm.nih.gov/pubmed/33028346
http://dx.doi.org/10.1186/s13014-020-01673-6