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Effects of U1 Small Nuclear Ribonucleoprotein Inhibition on the Expression of Genes Involved in Alzheimer’s Disease

[Image: see text] Deposition and dysfunction of U1 small nuclear ribonucleoprotein (snRNP) have been revealed in Alzheimer’s disease (AD), but whether U1 is involved in the amyloid precursor protein (APP) and Tau pathways remains unclear. Here, we investigate this by inhibiting the U1 components in...

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Detalles Bibliográficos
Autores principales: Zhu, Wenbo, Wei, Xuefei, Wang, Yanyang, Li, Jingjing, Peng, Lu, Zhang, Kui, Bai, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542834/
https://www.ncbi.nlm.nih.gov/pubmed/33043209
http://dx.doi.org/10.1021/acsomega.0c03568