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Regiospecific Synthesis and Structural Studies of 3,5-Dihydro-4H-pyrido[2,3-b][1,4]diazepin-4-ones and Comparison with 1,3-Dihydro-2H-benzo[b][1,4]diazepin-2-ones

[Image: see text] Nine 3,5-dihydro-4H-pyrido[2,3-b][1,4]diazepin-4-ones (17–25), some of which contain fluoro-substituents, have been regiospecifically prepared by reaction of 2,3-diaminopyridines with ethyl aroylacetates. In two cases, open intermediates have been isolated and these are related to...

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Detalles Bibliográficos
Autores principales: Núñez Alonso, David, Pérez-Torralba, Marta, Claramunt, Rosa M., Torralba, M. Carmen, Delgado-Martínez, Patricia, Alkorta, Ibon, Elguero, José, Roussel, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542844/
https://www.ncbi.nlm.nih.gov/pubmed/33043221
http://dx.doi.org/10.1021/acsomega.0c03843