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Clinical and molecular characterization of a multi-institutional cohort of pediatric spinal cord low-grade gliomas

BACKGROUND: The mitogen-activated protein kinases/extracelluar signal-regulated kinases pathway is involved in cell growth and proliferation, and mutations in BRAF have made it an oncogene of interest in pediatric cancer. Previous studies found that BRAF mutations as well as KIAA1549–BRAF fusions ar...

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Detalles Bibliográficos
Autores principales: Grob, Sydney T, Nobre, Liana, Campbell, Kristen R, Davies, Kurtis D, Ryall, Scott, Aisner, Dara L, Hoffman, Lindsey, Zahedi, Shadi, Morin, Andrew, Crespo, Michele, Nellan, Anandani, Green, Adam L, Foreman, Nicholas, Vibhakar, Rajeev, Hankinson, Todd C, Handler, Michael H, Hawkins, Cynthia, Tabori, Uri, Kleinschmidt-DeMasters, B K, Mulcahy Levy, Jean M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7542983/
https://www.ncbi.nlm.nih.gov/pubmed/33063010
http://dx.doi.org/10.1093/noajnl/vdaa103