Nonmuscle myosin 2 regulates cortical stability during sprouting angiogenesis

Among the three nonmuscle myosin 2 (NM2) paralogs, NM 2A and 2B, but not 2C, are detected in endothelial cells. To study the role of NM2 in vascular formation, we ablate NM2 in endothelial cells in mice. Ablating NM2A, but not NM2B, results in reduced blood vessel coverage and increased vascular bra...

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Detalles Bibliográficos
Autores principales: Ma, Xuefei, Uchida, Yutaka, Wei, Tingyi, Liu, Chengyu, Adams, Ralf H., Kubota, Yoshiaki, Gutkind, J. Silvio, Mukouyama, Yoh-suke, Adelstein, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543065/
https://www.ncbi.nlm.nih.gov/pubmed/32583739
http://dx.doi.org/10.1091/mbc.E20-03-0175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543065/
https://www.ncbi.nlm.nih.gov/pubmed/32583739
http://dx.doi.org/10.1091/mbc.E20-03-0175

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