Qki is an essential regulator of microglial phagocytosis in demyelination

The mechanism underpinning the regulation of microglial phagocytosis in demyelinating diseases is unclear. Here, we showed that the Quaking protein (Qki) in microglia was greatly induced by demyelination in the brains of both mice and humans. Deletion of the Quaking gene (Qk) in microglia severely i...

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Detalles Bibliográficos
Autores principales: Ren, Jiangong, Dai, Congxin, Zhou, Xin, Barnes, Joseph A., Chen, Xi, Wang, Yunfei, Yuan, Liang, Shingu, Takashi, Heimberger, Amy B., Chen, Yiwen, Hu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543092/
https://www.ncbi.nlm.nih.gov/pubmed/33045062
http://dx.doi.org/10.1084/jem.20190348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543092/
https://www.ncbi.nlm.nih.gov/pubmed/33045062
http://dx.doi.org/10.1084/jem.20190348

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