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Inhibition of overexpressed Kv3.4 augments HPV in endotoxemic mice
BACKGROUND: Hypoxic pulmonary vasoconstriction (HPV) is a reaction of the pulmonary vasculature upon hypoxia, diverting blood flow into ventilated areas to preserve oxygenation. It is impaired in endotoxemia or ARDS. Voltage gated potassium channels have been shown to play a key role in the regulati...
Autores principales: | Turzo, Maurizio, Metzger, Karin, Lasitschka, Felix, Weigand, Markus A., Busch, Cornelius J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543677/ https://www.ncbi.nlm.nih.gov/pubmed/33032555 http://dx.doi.org/10.1186/s12890-020-01278-5 |
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