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Immunoinformatics approach to understand molecular interaction between multi-epitopic regions of SARS-CoV-2 spike-protein with TLR4/MD-2 complex

BACKGROUND: The coronavirus (CoV) spike (S) protein is critical for receptor binding, membrane fusion and internalization of the virus into the human cells. We have tried to search the epitopic component of the S-protein that might be served as crucial targets for the vaccine development and also tr...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Manojit, Sharma, Ashish Ranjan, Mallick, Bidyut, Sharma, Garima, Lee, Sang-Soo, Chakraborty, Chiranjib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543713/
https://www.ncbi.nlm.nih.gov/pubmed/33039603
http://dx.doi.org/10.1016/j.meegid.2020.104587