Increased expression of serine palmitoyl transferase and ORMDL3 polymorphism are associated with eosinophilic inflammation and airflow limitation in aspirin-exacerbated respiratory disease

BACKGROUND: Patients with aspirin-exacerbated respiratory disease (AERD) are known to have poor clinical outcomes. The pathogenic mechanisms have not yet been completely understood. OBJECTIVE: We aimed to assess the involvement of the de-novo synthetic pathway of sphingolipid metabolism in patients...

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Detalles Bibliográficos
Autores principales: Ban, Ga-Young, Youn, Dong-Ye, Ye, Young-Min, Park, Hae-Sim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544079/
https://www.ncbi.nlm.nih.gov/pubmed/33031402
http://dx.doi.org/10.1371/journal.pone.0240334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544079/
https://www.ncbi.nlm.nih.gov/pubmed/33031402
http://dx.doi.org/10.1371/journal.pone.0240334

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