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Are long telomeres better than short? Relative contributions of genetically predicted telomere length to neoplastic and non-neoplastic disease risk and population health burden

BACKGROUND: Mendelian Randomization (MR) studies exploiting single nucleotide polymorphisms (SNPs) predictive of leukocyte telomere length (LTL) have suggested that shorter genetically determined telomere length (gTL) is associated with increased risks of degenerative diseases, including cardiovascu...

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Detalles Bibliográficos
Autores principales: Protsenko, Ekaterina, Rehkopf, David, Prather, Aric A., Epel, Elissa, Lin, Jue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544094/
https://www.ncbi.nlm.nih.gov/pubmed/33031470
http://dx.doi.org/10.1371/journal.pone.0240185