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Biological insights from multi-omic analysis of 31 genomic risk loci for adult hearing difficulty

Age-related hearing impairment (ARHI), one of the most common medical conditions, is strongly heritable, yet its genetic causes remain largely unknown. We conducted a meta-analysis of GWAS summary statistics from multiple hearing-related traits in the UK Biobank (n = up to 330,759) and identified 31...

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Detalles Bibliográficos
Autores principales: Kalra, Gurmannat, Milon, Beatrice, Casella, Alex M., Herb, Brian R., Humphries, Elizabeth, Song, Yang, Rose, Kevin P., Hertzano, Ronna, Ament, Seth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544108/
https://www.ncbi.nlm.nih.gov/pubmed/32986727
http://dx.doi.org/10.1371/journal.pgen.1009025