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Nuclear response to divergent mitochondrial DNA genotypes modulates the interferon immune response

Mitochondrial OXPHOS generates most of the energy required for cellular function. OXPHOS biogenesis requires the coordinated expression of the nuclear and mitochondrial genomes. This represents a unique challenge that highlights the importance of nuclear-mitochondrial genetic communication to cellul...

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Detalles Bibliográficos
Autores principales: Lopez Sanchez, M. Isabel G., Ziemann, Mark, Bachem, Annabell, Makam, Rahul, Crowston, Jonathan G., Pinkert, Carl A., McKenzie, Matthew, Bedoui, Sammy, Trounce, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544115/
https://www.ncbi.nlm.nih.gov/pubmed/33031404
http://dx.doi.org/10.1371/journal.pone.0239804