Cargando…
Nuclear response to divergent mitochondrial DNA genotypes modulates the interferon immune response
Mitochondrial OXPHOS generates most of the energy required for cellular function. OXPHOS biogenesis requires the coordinated expression of the nuclear and mitochondrial genomes. This represents a unique challenge that highlights the importance of nuclear-mitochondrial genetic communication to cellul...
Autores principales: | Lopez Sanchez, M. Isabel G., Ziemann, Mark, Bachem, Annabell, Makam, Rahul, Crowston, Jonathan G., Pinkert, Carl A., McKenzie, Matthew, Bedoui, Sammy, Trounce, Ian A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544115/ https://www.ncbi.nlm.nih.gov/pubmed/33031404 http://dx.doi.org/10.1371/journal.pone.0239804 |
Ejemplares similares
-
Cooperation between Monocyte-Derived Cells and Lymphoid Cells in the Acute Response to a Bacterial Lung Pathogen
por: Brown, Andrew S., et al.
Publicado: (2016) -
Mitochondrial DNA copy number is regulated in a tissue specific manner by DNA methylation of the nuclear-encoded DNA polymerase gamma A
por: Kelly, Richard D. W., et al.
Publicado: (2012) -
In Vivo IFN-γ Secretion by NK Cells in Response to Salmonella Typhimurium Requires NLRC4 Inflammasomes
por: Kupz, Andreas, et al.
Publicado: (2014) -
The response of hepatitis B virus genotype to interferon is associated with a mutation in the interferon-stimulated response element
por: Guo, Yanan, et al.
Publicado: (2019) -
STING-mediated type-I interferons contribute to the neuroinflammatory process and detrimental effects following traumatic brain injury
por: Abdullah, Amar, et al.
Publicado: (2018)