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Programmable cross-ribosome-binding sites to fine-tune the dynamic range of transcription factor-based biosensor

Currently, predictive translation tuning of regulatory elements to the desired output of transcription factor (TF)-based biosensors remains a challenge. The gene expression of a biosensor system must exhibit appropriate translation intensity, which is controlled by the ribosome-binding site (RBS), t...

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Detalles Bibliográficos
Autores principales: Ding, Nana, Yuan, Zhenqi, Zhang, Xiaojuan, Chen, Jing, Zhou, Shenghu, Deng, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544201/
https://www.ncbi.nlm.nih.gov/pubmed/32976557
http://dx.doi.org/10.1093/nar/gkaa786