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Programmable cross-ribosome-binding sites to fine-tune the dynamic range of transcription factor-based biosensor
Currently, predictive translation tuning of regulatory elements to the desired output of transcription factor (TF)-based biosensors remains a challenge. The gene expression of a biosensor system must exhibit appropriate translation intensity, which is controlled by the ribosome-binding site (RBS), t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544201/ https://www.ncbi.nlm.nih.gov/pubmed/32976557 http://dx.doi.org/10.1093/nar/gkaa786 |