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Post-translational modifications of hnRNP A1 differentially modulate retroviral IRES-mediated translation initiation

The full-length mRNAs of the human immunodeficiency virus type-1 (HIV-1), the human T-cell lymphotropic virus type-1 (HTLV-1), and the mouse mammary tumor virus (MMTV) harbor IRESs. The activity of the retroviral-IRESs requires IRES-transacting factors (ITAFs), being hnRNP A1, a known ITAF for the H...

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Detalles Bibliográficos
Autores principales: Barrera, Aldo, Ramos, Hade, Vera-Otarola, Jorge, Fernández-García, Leandro, Angulo, Jenniffer, Olguín, Valeria, Pino, Karla, Mouland, Andrew J, López-Lastra, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544202/
https://www.ncbi.nlm.nih.gov/pubmed/32960212
http://dx.doi.org/10.1093/nar/gkaa765