Histone chaperone FACT represses retrotransposon MERVL and MERVL-derived cryptic promoters

Endogenous retroviruses (ERVs) were usually silenced by various histone modifications on histone H3 variants and respective histone chaperones in embryonic stem cells (ESCs). However, it is still unknown whether chaperones of other histones could repress ERVs. Here, we show that H2A/H2B histone chap...

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Detalles Bibliográficos
Autores principales: Chen, Fuquan, Zhang, Weiyu, Xie, Dan, Gao, Tingting, Dong, Zhiqiang, Lu, Xinyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544220/
https://www.ncbi.nlm.nih.gov/pubmed/32894293
http://dx.doi.org/10.1093/nar/gkaa732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544220/
https://www.ncbi.nlm.nih.gov/pubmed/32894293
http://dx.doi.org/10.1093/nar/gkaa732

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