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The Bitome: digitized genomic features reveal fundamental genome organization

A genome contains the information underlying an organism's form and function. Yet, we lack formal framework to represent and study this information. Here, we introduce the Bitome, a matrix composed of binary digits (bits) representing the genomic positions of genomic features. We form a Bitome...

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Detalles Bibliográficos
Autores principales: Lamoureux, Cameron R, Choudhary, Kumari Sonal, King, Zachary A, Sandberg, Troy E, Gao, Ye, Sastry, Anand V, Phaneuf, Patrick V, Choe, Donghui, Cho, Byung-Kwan, Palsson, Bernhard O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544223/
https://www.ncbi.nlm.nih.gov/pubmed/32976587
http://dx.doi.org/10.1093/nar/gkaa774