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Comprehensive analysis of translation from overexpressed circular RNAs reveals pervasive translation from linear transcripts

Circular RNAs (circRNAs) encompass a widespread and conserved class of RNAs, which are generated by back-splicing of downstream 5′ to upstream 3′ splice sites. CircRNAs are tissue-specific and have been implicated in diseases including cancer. They can function as sponges for microRNAs (miRNAs) or R...

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Detalles Bibliográficos
Autores principales: Ho-Xuan, Hung, Glažar, Petar, Latini, Claudia, Heizler, Kevin, Haase, Jacob, Hett, Robert, Anders, Marvin, Weichmann, Franziska, Bruckmann, Astrid, Van den Berg, Debbie, Hüttelmaier, Stefan, Rajewsky, Nikolaus, Hackl, Christina, Meister, Gunter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544230/
https://www.ncbi.nlm.nih.gov/pubmed/32955563
http://dx.doi.org/10.1093/nar/gkaa704