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A super-sensitive auxin-inducible degron system with an engineered auxin-TIR1 pair

The auxin-inducible degron (AID) system enables rapid depletion of target proteins within the cell by applying the natural auxin IAA. The AID system is useful for investigating the physiological functions of essential proteins; however, this system generally requires high dose of auxin to achieve ef...

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Detalles Bibliográficos
Autores principales: Nishimura, Kohei, Yamada, Ryotaro, Hagihara, Shinya, Iwasaki, Rie, Uchida, Naoyuki, Kamura, Takumi, Takahashi, Koji, Torii, Keiko U, Fukagawa, Tatsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544234/
https://www.ncbi.nlm.nih.gov/pubmed/32941625
http://dx.doi.org/10.1093/nar/gkaa748