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Repurposing of KLF5 activates a cell cycle signature during the progression from a precursor state to oesophageal adenocarcinoma
Oesophageal adenocarcinoma (OAC) is one of the most common causes of cancer deaths. Barrett’s oesophagus (BO) is the only known precancerous precursor to OAC, but our understanding about the molecular events leading to OAC development is limited. Here, we have integrated gene expression and chromati...
Autores principales: | Rogerson, Connor, Ogden, Samuel, Britton, Edward, Ang, Yeng, Sharrocks, Andrew D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544504/ https://www.ncbi.nlm.nih.gov/pubmed/32880368 http://dx.doi.org/10.7554/eLife.57189 |
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