PLK-1 promotes the merger of the parental genome into a single nucleus by triggering lamina disassembly

Life of sexually reproducing organisms starts with the fusion of the haploid egg and sperm gametes to form the genome of a new diploid organism. Using the newly fertilized Caenorhabditis elegans zygote, we show that the mitotic Polo-like kinase PLK-1 phosphorylates the lamin LMN-1 to promote timely...

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Detalles Bibliográficos
Autores principales: Velez-Aguilera, Griselda, Nkombo Nkoula, Sylvia, Ossareh-Nazari, Batool, Link, Jana, Paouneskou, Dimitra, Van Hove, Lucie, Joly, Nicolas, Tavernier, Nicolas, Verbavatz, Jean-Marc, Jantsch, Verena, Pintard, Lionel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544505/
https://www.ncbi.nlm.nih.gov/pubmed/33030429
http://dx.doi.org/10.7554/eLife.59510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544505/
https://www.ncbi.nlm.nih.gov/pubmed/33030429
http://dx.doi.org/10.7554/eLife.59510

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