Genome-wide effects of the antimicrobial peptide apidaecin on translation termination in bacteria

Biochemical studies suggested that the antimicrobial peptide apidaecin (Api) inhibits protein synthesis by binding in the nascent peptide exit tunnel and trapping the release factor associated with a terminating ribosome. The mode of Api action in bacterial cells had remained unknown. Here genome-wi...

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Detalles Bibliográficos
Autores principales: Mangano, Kyle, Florin, Tanja, Shao, Xinhao, Klepacki, Dorota, Chelysheva, Irina, Ignatova, Zoya, Gao, Yu, Mankin, Alexander S, Vázquez-Laslop, Nora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544508/
https://www.ncbi.nlm.nih.gov/pubmed/33031031
http://dx.doi.org/10.7554/eLife.62655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544508/
https://www.ncbi.nlm.nih.gov/pubmed/33031031
http://dx.doi.org/10.7554/eLife.62655

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