The DANish randomized, double-blind, placebo controlled trial in patients with chronic HEART failure (DANHEART): A 2 × 2 factorial trial of hydralazine-isosorbide dinitrate in patients with chronic heart failure (H-HeFT) and metformin in patients with chronic heart failure and diabetes or prediabetes (Met-HeFT)

OBJECTIVES: The DANHEART trial is a multicenter, randomized (1:1), parallel-group, double-blind, placebo-controlled study in chronic heart failure patients with reduced ejection fraction (HFrEF). This investigator driven study will include 1500 HFrEF patients and test in a 2 × 2 factorial design: 1)...

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Detalles Bibliográficos
Autores principales: Wiggers, Henrik, Køber, Lars, Gislason, Gunnar, Schou, Morten, Poulsen, Mikael Kjær, Vraa, Søren, Nielsen, Olav Wendelbo, Bruun, Niels Eske, Nørrelund, Helene, Hollingdal, Malene, Barasa, Anders, Bøttcher, Morten, Dodt, Karen, Hansen, Vibeke Brogaard, Nielsen, Gitte, Knudsen, Anne Sejr, Lomholdt, Jens, Mikkelsen, Kirsten Vilain, Jonczy, Bartlomiej, Brønnum-Schou, Jens, Poenaru, Monica Petronela, Abdulla, Jawdat, Raymond, Ilan, Mahboubi, Kiomars, Sillesen, Karen, Serup-Hansen, Kristine, Madsen, Jette Sandberg, Kristensen, Søren Lund, Larsen, Anders Hostrup, Bøtker, Hans Erik, Torp-Petersen, Christian, Eiskjær, Hans, Møller, Jacob, Hassager, Christian, Steffensen, Flemming Hald, Bibby, Bo Martin, Refsgaard, Jens, Høfsten, Dan Eik, Mellemkjær, Søren, Gustafsson, Finn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Trial Designs
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544566/
https://www.ncbi.nlm.nih.gov/pubmed/33039340
http://dx.doi.org/10.1016/j.ahj.2020.09.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544566/
https://www.ncbi.nlm.nih.gov/pubmed/33039340
http://dx.doi.org/10.1016/j.ahj.2020.09.020

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