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Detection of genomic alterations in breast cancer with circulating tumour DNA sequencing

Analysis of circulating cell-free DNA (cfDNA) has opened new opportunities for characterizing tumour mutational landscapes with many applications in genomic-driven oncology. We developed a customized targeted cfDNA sequencing approach for breast cancer (BC) using unique molecular identifiers (UMIs)...

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Detalles Bibliográficos
Autores principales: Kleftogiannis, Dimitrios, Ho, Danliang, Liew, Jun Xian, Poon, Polly S. Y., Gan, Anna, Ng, Raymond Chee-Hui, Tan, Benita Kiat-Tee, Tay, Kiang Hiong, Lim, Swee H., Tan, Gek San, Shih, Chih Chuan, Lim, Tony Kiat-Hon, Lee, Ann Siew-Gek, Tan, Iain Beehuat, Yap, Yoon-Sim, Ng, Sarah B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544894/
https://www.ncbi.nlm.nih.gov/pubmed/33033274
http://dx.doi.org/10.1038/s41598-020-72818-6