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Detection of genomic alterations in breast cancer with circulating tumour DNA sequencing
Analysis of circulating cell-free DNA (cfDNA) has opened new opportunities for characterizing tumour mutational landscapes with many applications in genomic-driven oncology. We developed a customized targeted cfDNA sequencing approach for breast cancer (BC) using unique molecular identifiers (UMIs)...
Autores principales: | Kleftogiannis, Dimitrios, Ho, Danliang, Liew, Jun Xian, Poon, Polly S. Y., Gan, Anna, Ng, Raymond Chee-Hui, Tan, Benita Kiat-Tee, Tay, Kiang Hiong, Lim, Swee H., Tan, Gek San, Shih, Chih Chuan, Lim, Tony Kiat-Hon, Lee, Ann Siew-Gek, Tan, Iain Beehuat, Yap, Yoon-Sim, Ng, Sarah B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544894/ https://www.ncbi.nlm.nih.gov/pubmed/33033274 http://dx.doi.org/10.1038/s41598-020-72818-6 |
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