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Titrating bacterial growth and chemical biosynthesis for efficient N-acetylglucosamine and N-acetylneuraminic acid bioproduction

Metabolic engineering facilitates chemical biosynthesis by rewiring cellular resources to produce target compounds. However, an imbalance between cell growth and bioproduction often reduces production efficiency. Genetic code expansion (GCE)-based orthogonal translation systems incorporating non-can...

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Detalles Bibliográficos
Autores principales: Tian, Rongzhen, Liu, Yanfeng, Cao, Yanting, Zhang, Zhongjie, Li, Jianghua, Liu, Long, Du, Guocheng, Chen, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544899/
https://www.ncbi.nlm.nih.gov/pubmed/33033266
http://dx.doi.org/10.1038/s41467-020-18960-1