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Potential mechanism underlying the effect of matrine on COVID-19 patients revealed through network pharmacological approaches and molecular docking analysis

BACKGROUND: The clinical efficacy of matrine in treating coronavirus disease (COVID-19) has been confirmed; however, its underlying mechanism of action remains unknown. METHODS: TCMSP, SwissTargetPrediction, SEA, GeneCards, CTD, and TTD were used to identify potential targets for matrine in SARS-CoV...

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Detalles Bibliográficos
Autores principales: Peng, Wenpan, Xu, Yong, Han, Di, Feng, Fanchao, Wang, Zhichao, Gu, Cheng, Zhou, Xianmei, Wu, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544918/
https://www.ncbi.nlm.nih.gov/pubmed/32915649
http://dx.doi.org/10.1080/13813455.2020.1817944