Spatiotemporal PET Imaging Reveals Differences in CAR-T Tumor Retention in Triple-Negative Breast Cancer Models

Chimeric antigen receptor T cell therapy (CAR-T) has been rolled out as a new treatment for hematological malignancies. For solid tumor treatment, CAR-T has been disappointing so far. Challenges include the quantification of CAR-T trafficking, expansion and retention in tumors, activity at target si...

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Detalles Bibliográficos
Autores principales: Volpe, Alessia, Lang, Cameron, Lim, Lindsay, Man, Francis, Kurtys, Ewelina, Ashmore-Harris, Candice, Johnson, Preeth, Skourti, Elena, de Rosales, Rafael T.M., Fruhwirth, Gilbert O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544977/
https://www.ncbi.nlm.nih.gov/pubmed/32645298
http://dx.doi.org/10.1016/j.ymthe.2020.06.028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544977/
https://www.ncbi.nlm.nih.gov/pubmed/32645298
http://dx.doi.org/10.1016/j.ymthe.2020.06.028

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