Long Noncoding RNA OIP5-AS1 Inhibits Cell Apoptosis and Cataract Formation by Blocking POLG Expression Under Oxidative Stress

PURPOSE: Cataract, a clouding of the intraocular lens, is the leading cause of blindness. The lens-expressed long noncoding RNA OIP5-AS1 was upregulated in lens epithelial cells from patients with cataracts, suggesting its pathogenic role in cataracts. We investigated the regulatory role of OIP5-AS1...

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Detalles Bibliográficos
Autores principales: Jing, Ruihua, Ma, Bo, Qi, Tiantian, Hu, Conghui, Liao, Chongbing, Wen, Chan, Shao, Yongping, Pei, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Biochemistry and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545078/
https://www.ncbi.nlm.nih.gov/pubmed/33006594
http://dx.doi.org/10.1167/iovs.61.12.3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545078/
https://www.ncbi.nlm.nih.gov/pubmed/33006594
http://dx.doi.org/10.1167/iovs.61.12.3

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