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Astrocytes regulate brain extracellular pH via a neuronal activity-dependent bicarbonate shuttle
Brain cells continuously produce and release protons into the extracellular space, with the rate of acid production corresponding to the levels of neuronal activity and metabolism. Efficient buffering and removal of excess H(+) is essential for brain function, not least because all the electrogenic...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545092/ https://www.ncbi.nlm.nih.gov/pubmed/33033238 http://dx.doi.org/10.1038/s41467-020-18756-3 |