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A gene expression signature of TREM2(hi) macrophages and γδ T cells predicts immunotherapy response

Identifying factors underlying resistance to immune checkpoint therapy (ICT) is still challenging. Most cancer patients do not respond to ICT and the availability of the predictive biomarkers is limited. Here, we re-analyze a publicly available single-cell RNA sequencing (scRNA-seq) dataset of melan...

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Detalles Bibliográficos
Autores principales: Xiong, Donghai, Wang, Yian, You, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545100/
https://www.ncbi.nlm.nih.gov/pubmed/33033253
http://dx.doi.org/10.1038/s41467-020-18546-x