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Prostate cancer evolution from multilineage primary to single lineage metastases with implications for liquid biopsy
The evolutionary progression from primary to metastatic prostate cancer is largely uncharted, and the implications for liquid biopsy are unexplored. We infer detailed reconstructions of tumor phylogenies in ten prostate cancer patients with fatal disease, and investigate them in conjunction with his...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545111/ https://www.ncbi.nlm.nih.gov/pubmed/33033260 http://dx.doi.org/10.1038/s41467-020-18843-5 |