Prostate cancer evolution from multilineage primary to single lineage metastases with implications for liquid biopsy

The evolutionary progression from primary to metastatic prostate cancer is largely uncharted, and the implications for liquid biopsy are unexplored. We infer detailed reconstructions of tumor phylogenies in ten prostate cancer patients with fatal disease, and investigate them in conjunction with his...

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Detalles Bibliográficos
Autores principales: Woodcock, D. J., Riabchenko, E., Taavitsainen, S., Kankainen, M., Gundem, G., Brewer, D. S., Ellonen, P., Lepistö, M., Golubeva, Y. A., Warner, A. C., Tolonen, T., Jasu, J., Isaacs, W. B., Emmert-Buck, M. R., Nykter, M., Visakorpi, T., Bova, G. S., Wedge, D. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545111/
https://www.ncbi.nlm.nih.gov/pubmed/33033260
http://dx.doi.org/10.1038/s41467-020-18843-5

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